1.During which phase(s) of cell cycle, the amount of DNA in a cell remains at 4C level if the initial amount is denoted as 2C?- (1)G0 and G1
- (2)G1 and S
- (3)Only G2
- (4)G2 and M
2.Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain associated at their centromeres:- (1)Metaphase II
- (2)Anaphase I
- (3)Anaphase II
- (4)Metaphase I
3.In meiosis crossing over is initiated at:- (1)Pachytene
- (2)Leptotene
- (3)Zygotene
- (4)Diplotene
4.Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?- (1)Chromosomes will be fragmented
- (2)Chromosomes will not segregate
- (3)Recombination of chromosome arms will occur
- (4)Chromosomes will not condense
5.Which of the following is not characteristic feature during mitosis in somatic cells?- (1)Spindle fibres
- (2)Disappearance of nucleolus
- (3)Chromosome movement
- (4)Synapsis
6.Which stage of meiosis can last for months or years in the oocytes of some verterbrates?- (1)Leptotene
- (2)Pachytene
- (3)Diplotene
- (4)Diakinesis
7.In a mitotic cycle, the correct sequence of phases is- (1)S, G1, G2, M
- (2)G1, S, G2, M
- (3)M, G1, G2, S
- (4)G1, G2, S, M
8.During mitosis ER and nucleolus begin to disappear at :- (1)Early prophase
- (2)Late prophase
- (3)Early metaphase
- (4)Late metaphase
9.Among eukaryotes, replication of DNA takes place in- (1)G2 phase
- (2)M phase
- (3)S phase
- (4)G1 phase
10.An elaborate network of filamentous proteinaceous structures present in the cytoplasm which helps in the maintenance of cell shape is called- (1)Thylakoid
- (2)Endoplasmic reticulum
- (3)Plasmalemma
- (4)Cytoskeleton
11.Which stage of meiotic prophase shows terminalisation of chiasmata as its distinctive feature?- (1)Zygotene
- (2)Diakinesis
- (3)Pachytene
- (4)Leptotene
12.The enzyme recombinase is required at which stage of meiosis:- (1)Pachytene
- (2)Zygotene
- (3)Diplotene
- (4)Diakinesis
13.Regarding Meiosis, which of the statements is incorrect?- (1)Four haploid cells are formed at the end of Meiosis-II
- (2)There are two stages in Meiosis, Meiosis-I and II
- (3)DNA replication occurs in S phase of Meiosis-II
- (4)Pairing of homologous chromosomes and recombination occurs in Meiosis-I
14.During gamete formation the enzyme recombinase participates during- (1)Metaphase I
- (2)Anaphase II
- (3)Prophase I
- (4)Prophase II
15.Which of the following stages of meiosis involves division of centromere?- (1)Telophase
- (2)Metaphase I
- (3)Metaphase II
- (4)Anaphase II
16.Attachment of spindle fibers to kinetochores of chromosomes becomes evident in- (1)Telophase
- (2)Prophase
- (3)Metaphase
- (4)Anaphase
17.Identify the correct statement with regard to G1 phase (Gap1) of interphase.- (1)Nuclear Division takes place.
- (2)DNA synthesis or replication takes place.
- (3)Reorganisation of all cell components takes place.
- (4)Cell is metabolically active, grows but does not replicate its DNA.
18.Which one of the following never occurs during mitotic cell division?- (1)Coiling and condensation of the chromatids
- (2)Spindle fibres attach to kinetochores of chromosomes
- (3)Movement of centrioles towards opposite poles
- (4)Pairing of homologous chromosomes
19.A somatic cell that has just completed the S phase of its cell cycle when compared to the gamete of the same species has- (1)Twice the number of chromosomes and twice the amount of DNA.
- (2)Same number of chromosomes but twice the amount of DNA.
- (3)Twice the number of chromosomes and four times the amount of DNA.
- (4)Four times the number of chromosomes and twice the amount of DNA.
20.Select the incorrect statement with reference to mitosis:- (1)Splitting of centromere occurs at anaphase
- (2)All the chromosomes lie at the equator at metaphase
- (3)Spindle fibres attach to centromere of chromosomes
- (4)Chromosomes decondense at telophase
21.Some dividing cells exit the cell cycle and enter vegetative inactive stage. This is called quiescent stage (G0). This process occurs at the end of- (1)G1-phase
- (2)S-phase
- (3)G2-phase
- (4)M-phase
22.Dissolution of the synaptonemal complex occurs during- (1)Zygotene
- (2)Diplotene
- (3)Leptotene
- (4)Pachytene
23.The process of appearance of recombination nodules occurs at which sub stage of prophase I in meiosis?- (1)Diakinesis
- (2)Pachytene
- (3)Zygotene
- (4)Diplotenes
24.Which is incorrect statement about meiosis?- (1)Meiosis involves two sequential cycles of nuclear and cell division called meiosis I and meiosis II but only a single cycle of DNA replication.
- (2)Meiosis I is initiated after parental chromosome have replicated to produce sister chromatids at the S phase.
- (3)Meiosis involves pairing of nonhomologous chromosomes and recombination between them.
- (4)Four haploid cells are formed at the end of meiosis-II.
25.During Meiosis-I, in which stage synapsis takes place?- (1)Pachytene
- (2)Zygotene
- (3)Diplotene
- (4)Leptotene
26.The synaptonemal complex formed by a pair of synapsed homologous chromosomes is called- (1)Bivalent
- (2)Tetravalent
- (3)Tetrad
- (4)Both (a) and (c)
27.Which of the following options gives the correct sequence of events during mitosis ?- (1)Condensation → nuclear membrane disassembly → arrangement at equator → centromere division → segregation → telophase
- (2)Condensation → crossing over → nuclear membrane disassembly → segregation → telophase
- (3)Condensation → arrangement at equator → centromere division → segregation → telophase
- (4)Condensation → nuclear membrane disassembly → crossing over → segregation → telophase
28.The complex formed by a pair of synapsed homologous chromosomes is called- (1)Equatorial plate
- (2)Kinetochore
- (3)Bivalent
- (4)Axoneme
29.During mitosis the ER and nucleolus begins to disappear at- (1)Late prophase
- (2)Early metaphase
- (3)Late metaphase
- (4)Early prophase
30.The centriole undergoes duplication during- (1)Prophase
- (2)Metaphase
- (3)G2-phase
- (4)S-phase
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