NEET Previous Year Question

Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?

Topic: NEET PYQ

Answer: B. Full step-by-step solution below.

  1. AChromosomes will be fragmented
  2. BChromosomes will not segregate
  3. CRecombination of chromosome arms will occur
  4. DChromosomes will not condense

Correct answer: B

Solution

(b) The Anaphase Promoting Complex (APC) is required for the transition from metaphase to anaphase. It promotes separation of sister chromatids. If APC is defective, sister chromatids cannot separate and chromosomes will not segregate to opposite poles.

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