NEET Previous Year Question

Under which of the following conditions will there be no change in the reading frame of following mRNA ? 5'AACAGCGGUGCUAUU3'

Topic: NEET PYQ

Answer: D. Full step-by-step solution below.

  1. AInsertion of G at 5th position
  2. BDeletion of G from 5th position
  3. CInsertion of A and G and 4th and positions respectively
  4. DDeletion of GGU from 7th, 8th and positions

Correct answer: D

Solution

(d) Reading frame changes occur when bases are added or removed not in multiples of 3.
(a) Insertion of 1 base → Frameshift
(b) Deletion of 1 base → Frameshift
(c) Insertion of 2 bases → Frameshift
(d) Deletion of 3 bases (GGU) → No frameshift

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