Molecular Basis of Inheritance PYQs Set 1 (PDF)

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Mere Teacher · Previous Year Questions NEET Biology · Molecular Basis of Inheritance · Set 1 (Q1-30)
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1. $If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6 \times 10^{9} bp, then the length of the DNA is approximately:$ (1) $2.5 meters$ (2) $2.2 meters$ (3) $2.7 meters$ (4) $2.0 meters$ 2. $Which of the following RNAs should be most abundant in animal cell?$ (1) $t-RNA$ (2) $m-RNA$ (3) $mi-RNA$ (4) $r-RNA$ 3. $The one aspect which is not a salient feature of genetic code is its being$ (1) $Degenerate$ (2) $Ambiguous$ (3) $Universal$ (4) $Specific$ 4. $Removal of RNA polymerase III from nucleoplasm will affect the synthesis of$ (1) $tRNA$ (2) $hnRNA$ (3) $mRNA$ (4) $rRNA$ 5. $What is the role of RNA polymerase III in the process of transcription in eukaryotes?$ (1) $Transcribes rRNAs (28S, 18S and 5.8S)$ (2) $Transcribes tRNA, 5s rRNA and snRNA$ (3) $Transcribes precursor of mRNA$ (4) $Transcribes only snRNAs$ 6. $Expressed Sequence Tags (ESTs) refers to:$ (1) $Genes expressed as RNA$ (2) $Polypeptide expression$ (3) $DNA polymorphism$ (4) $Novel DNA sequences$ 7. $Under which of the following conditions will there be no change in the reading frame of following mRNA ? 5'AACAGCGGUGCUAUU3'$ (1) $Insertion of G at 5th position$ (2) $Deletion of G from 5th position$ (3) $Insertion of A and G and 4th and 5^{t h} positions respectively$ (4) $Deletion of GGU from 7th, 8th and 9^{t h} positions$ 8. $In sea urchin DNA, which is double stranded, 17% of the bases were shown to be cytosine. The percentages of the other three bases expected to be present in this DNA are :$ (1) $G 34%, A 24.5%, T 24.5%$ (2) $G 17%, A 16.5%, T 32.5%$ (3) $G 17%, A 33%, T 33%$ (4) $G 8.5%, A 50%, T 24.5%$ 9. $From the following, identify the correct combination of salient features of Genetic Code :-$ (1) $Universal, Non-ambiguous, Overlapping$ (2) $Degenerate, Overlapping, Commaless$ (3) $Universal, Ambiguous, Degenerate$ (4) $Degenerate, Non-overlapping, Nonambiguous$ 10. $Which one of the following is the starter codon?$ (1) $AUG$ (2) $UGA$ (3) $UAA$ (4) $UAG$ 11. $Which of the following rRNAs acts a structural RNA as well as ribozyme in bacteria?$ (1) $18 S rRNA$ (2) $23 S rRNA$ (3) $5.8 S rRNA$ (4) $5 S rRNA$ 12. $Which is the "Only enzyme" that has "Capability" to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?$ (1) $DNA dependent RNA polymerase$ (2) $DNA Ligase$ (3) $DNase$ (4) $DNA dependent DNA polymerase$ 13. $Which one of the following statements about Histones is wrong?$ (1) $Histones are organized to form a unit of 8 molecules.$ (2) $The pH of histones is slightly acidic.$ (3) $Histones are rich in amino acids - Lysine and Arginine.$ (4) $Histones carry positive charge in the side chain.$ 14. $Which of the following is not required for any of the techniques of DNA fingerprinting available at present?$ (1) $Polymerase chain reaction$ (2) $Zinc figure analysis$ (3) $Restriction enzymes$ (4) $DNA - DNA hybridization$ 15. $An analysis of chromosomal DNA using the Southern hybridization technique does not use$ (1) $Electrophoresis$ (2) $Blotting$ (3) $Autoradiography$ (4) $PCR$ 16. $With respect to nucleosome, which of the following statements is incorrect?$ (1) $Nucleosomes are seen as ‘beads on string’ under Electron Microscope$ (2) $DNA is wrapped around positively charged histone octamer to form nucleosome.$ (3) $Nucleosome is the repeating unit of chromatin$ (4) $Nucleosome contains 120 bp of DNA helix$ 17. $Which one of the following experiments of Frederick Griffith resulted in the discovery of bacterial transformation?$ (1) $S-strain (heat killed) + R-strain (live) \to injected in to Mice \to Mice died$ (2) $S-strain \to injected in to Mice \to Mice died$ (3) $R-strain \to injected in to Mice \to Mice lived$ (4) $S-strain (heat killed) \to injected in to Mice \to Mice lived$ 18. $Identify the correct order of organization of genetic material from largest to smallest:$ (1) $Genome, chromosome, nucleotide, gene$ (2) $Genome, chromosome, gene, nucleotide$ (3) $Chromosome, genome, nucleotide, gene$ (4) $Chromosome, gene, genome, nucleotide$ 19. $Which of the following nitrogen base is not found in DNA-$ (1) $Thymine$ (2) $Cytosine$ (3) $Guanine$ (4) $Uracil$ 20. $The Okazaki fragments in DNA chain growth :$ (1) $Result in transcription$ (2) $Polymerize in the 3'-to-5' direction and forms replication fork$ (3) $Prove semi-conservative nature of DNA replication$ (4) $Polymerize in the 5'-to-3' direction and explain 3'-to-5' DNA replication$ 21. $What is it that forms the basis of DNA Fingerprinting?$ (1) $The relative amount of DNA in the ridges and grooves of the fingerprints.$ (2) $Satellite DNA occurring as highly repeated short DNA segments$ (3) $The relative proportions of purines and pyrimidines in DNA$ (4) $The relative difference in the DNA occurence in blood, skin and saliva$ 22. $Identify the correct order of organisation of genetic material from largest to smallest :$ (1) $Chromosome, genome, nucleotide, gene$ (2) $Chromosome, gene, genome, nucleotide$ (3) $Genome, chromosome, nucleotide, gene$ (4) $Genome, chromosome, gene, nucleotide$ 23. $Amino acid sequence, in protein synthesis is decided by the sequence of$ (1) $tRNA$ (2) $mRNA$ (3) $cDNA$ (4) $rRNA$ 24. $The process of translation of mRNA to proteins begins as soon as:$ (1) $The tRNA is activated and the larger subunit of ribosome encounters mRNA$ (2) $The small subunit of ribosome encounters mRNA$ (3) $The larger subunit of ribosome encounters mRNA$ (4) $Both the subunits join together to bind with mRNA$ 25. $Taylor conducted the experiment to prove semiconservative mode of chromosome replication on :$ (1) $Drosophila melanogaster$ (2) $E. coli$ (3) $Vinca rosea$ (4) $Vicia faba$ 26. $Which one of the following is not applicable to RNA?$ (1) $5’ phosphoryl and 3’hydroxyl ends$ (2) $Heterocyclic nitrogenous bases$ (3) $Chargaff’s rule$ (4) $Complementary base pairing$ 27. $Name the enzyme that facilitates opening of DNA helix during transcription.$ (1) $DNA helicase$ (2) $DNA polymerase$ (3) $RNA polymerase$ (4) $DNA ligase$ 28. $Which of the following is required as inducer(s) for the expression of Lac operon?$ (1) $Glucose$ (2) $Galactose$ (3) $Lactose$ (4) $Lactose and galactose$ 29. $If one strand of DNA has the nitrogenous base sequence as ATCTG, then what would be the complementary RNA strand sequence?$ (1) $TTAGU$ (2) $UAGAC$ (3) $AACTG$ (4) $ATCGU$ 30. $Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?$ (1) $AUG,ACG - Start/Methionine$ (2) $UUA, UCA -Leucine$ (3) $GUU, GCU -Alanine$ (4) $UAG, UGA - Stop$