91.Which of the following bond is not related to nucleic acid :- (1)H-bond
- (2)Ester bond
- (3)Glycosidic bond
- (4)Peptide bond
92.If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?- (1)11
- (2)33
- (3)333
- (4)1
93.Which of the following step is not involved in Southern blot hybridisation?- (1)Electrophoresis
- (2)Autoradiography
- (3)Hybridisation
- (4)Mutation
94.Which of the following biomolecules does have a phosphodiester bond?- (1)Nucleic acids in a nucleotide
- (2)Fatty acids in a diglyceride
- (3)Monosaccharides in a polysaccharide
- (4)Amino acids in a polypeptide
95.AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?- (1)AGGUAUCGCAU
- (2)UGGTUTCGCAT
- (3)ACCUAUGCGAU
- (4)UCCAUAGCGUA
96.The association of histone H1 with a nucleosome indicates:- (1)DNA replication is occurring.
- (2)The DNA is condensed into a Chromatin Fibre.
- (3)The DNA double helix is exposed.
- (4)Transcription is occurring.
97.The mechanism that causes a gene to move from one linkage group to another is called:- (1)Translocation
- (2)Crossing-over
- (3)Inversion
- (4)Duplication
98.Expressed Sequence Tags (ESTs) refers to- (1)Certain important expressed genes.
- (2)All genes that are expressed as RNA.
- (3)All genes that are expressed as proteins.
- (4)All genes whether expressed or unexpressed.
99.What will be the sequence of mRNA produced by the following stretch of DNA ? 3'ATGCATGCATGCATG5' TEMPLATE STRAND 5'TACGTACGTACGTAC3' CODING STRAND- (1)3'AUGCAUGCAUGCAUG5'
- (2)5'UACGUACGUACGUAC3'
- (3)3'UACGUACGUACGUAC5'
- (4)5'AUGCAUGCAUGCAUG3'
100.Removal of introns and joining of exons in a defined order during transcription is called- (1)Looping
- (2)Inducing
- (3)Slicing
- (4)Splicing
101.Unequivocal proof that DNA is the genetic material was first proposed by- (1)Wilkins and Franklin
- (2)Fedrick, Griffith
- (3)Alfred Hershey and Martha Chase
- (4)Avery, MacLeod and McCarthy
102.How many different proteins does the ribosome consist of?- (1)20
- (2)80
- (3)60
- (4)40
103.Semiconservative replication of DNA was first demonstrated in :-- (1)Salmonella typhimurium
- (2)Drosophila melanogaster
- (3)Escherichia coli
- (4)Streptococcus pneumoniae
104.If A and C make 30% and 20% of DNA, respectively, what will be the percentage composition of T and G?- (1)T : 20%, G : 30%
- (2)T : 30%, G : 20%
- (3)T : 30%, G : 30%
- (4)T : 20%, G : 20%
105.Which one of the following is not a criterion of genetic material?- (1)Should be able to express itself in the form of Mendelian character.
- (2)Should be able to generate its replica.
- (3)Should be stable chemically and structurally.
- (4)Should not provide the scope for changes for evolution
106.The unequivocal proof of DNA as the genetic material came from the studies on a- (1)Bacterium
- (2)Fungus
- (3)Viroid
- (4)Bacterial virus
107.What is the role of RNA ploymerase III in the process of transcription in eukaryotes?- (1)Transcribes tRNA, 5s rRNA and sn RNA
- (2)Transcribes precursor of mRNA
- (3)Transcribes only snRNAs
- (4)Transcribes rRNAs (28S, 18S and 5.8S)
108.What would be the proportions of light and hybrid density DNA molecule, respectively if Meselson and Stahl's experiment was continued for 60 minutes?- (1)25%, 75%
- (2)75%, 25%
- (3)100%, 0%
- (4)50%, 50
109.The experimental proof for semiconservative replication of DNA was first shown in a- (1)Fungus
- (2)Bacterium
- (3)Plant
- (4)Virus
110.Haploids are more suitable for mutation studies than the diploids. This is because :-- (1)haploids are more abundant in nature than diploids
- (2)All mutations, whether dominant or recessive are expressed in haploids
- (3)Haploids are reproductively more stable than diploids
- (4)Mutagens penetrate in haploids more effectively than in diploids
111.During DNA replication, Okazaki fragmentsare used to elongate:- (1)The lagging strand towards replication fork.
- (2)The leading strand away from replication fork.
- (3)The lagging strand away from the replication fork.
- (4)The leading strand towards replication fork.
112.The 3′ – 5′ phosphodiester linkages inside a polynucleotide chain serve to join- (1)One DNA strand with the other DNA strand.
- (2)One nucleoside with another nucleoside.
- (3)One nucleotide with another nucleotide.
- (4)One nitrogenous base with pentose sugar
113.Under which of the following conditions will there be no change in the reading frame of following mRNA? 5'AACAGCGGUGCUAUU3'- (1)Insertion of G at 5th position
- (2)Deletion of G from 5th position
- (3)Insertion of A and G at 4th and 5th positions respectively
- (4)Deletion of GGU from 7th,8th and 9th positions
114.A non-proteinaceous enzyme is :-- (1)Ligase
- (2)Deoxyribonuclease
- (3)Lysozyme
- (4)Ribozyme
115.Transformation was discovered by- (1)Meselson and Stahl
- (2)Hershey and Chase
- (3)Griffith
- (4)Watson and Crick
116.Polysome is formed by :-- (1)A ribosome with several subunits
- (2)Ribosomes attached to each other in a linear arrangement
- (3)Several ribosomes attached to a single mRNA
- (4)Many ribosomes attached to a strand of endoplasmic reticulum
117.Identify the correct statement.- (1)RNA polymerase binds with Rho factor to terminate the process of transcription in bacteria.
- (2)The coding strand in transcription unit is copied to an mRNA.
- (3)Split gene arrangement is characteristic of prokaryotes.
- (4)In capping, methyl guanosine triphosphate is added to the 3’ end of hnRNA.
118.Satellite DNA is important because it :- (1)Codes for enzymes needed for DNA replication
- (2)Codes for proteins needed in cell cycle
- (3)Shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children
- (4)Does not code for proteins and is same in all members of the population
119.The first phase of translation is :- (1)Recognition of an anti-codon
- (2)Binding of mRNA to ribosome
- (3)Recognition of DNA molecule
- (4)Aminoacylation of tRNA
120.Select the correct match :- (1)Alec Jeffreys – Streptococcus pneumoniae
- (2)Alfred Hershey and – TMV Martha Chase
- (3)Matthew Meselson – Pisum sativum and F. Stahl
- (4)Francois Jacob and – Lac operon Jacques Monod
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