61.Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet" :-- (1)Beadle and tatum
- (2)Nirenberg and Mathaei
- (3)Hershey and Chase
- (4)Morgan and Sturtevant
62.Differentiation of organs and tissues in a developing organism, is association with :-- (1)Developmental mutations
- (2)Differential expression of genes
- (3)Lethal mutations
- (4)Deletion of genes
63.The recombination frequency between the genes (A) & (C) is 5%, (B) & (C) is 15%, (B) & (D) is 9%, (A) & (B) is 20%, (C) & (D) is 24% and (A) & (D) is 29%. What will be the sequence of these genes on a linear chromosome?- (1)(A), (C), (B), (D)
- (2)(A), (D), (B), (C)
- (3)(D), (B), (A), (C)
- (4)(A), (B), (C), (D)
64.If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as:- (1)Bioinformatics
- (2)Sequence annotation
- (3)Gene mapping
- (4)Expressed sequence tags
65.Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria?- (1)23 S rRNA
- (2)5.8 S rRNA
- (3)5 S rRNA
- (4)18 S rRNA
66.In the polynucleotide chain of DNA, a nitrogenous base is linked to the -OH of:- (1)3’C pentose sugar
- (2)5’C pentose sugar
- (3)1’C pentose sugar
- (4)2’C pentose sugar
67.In gel electrophoresis, separated DNA fragments can be visualized with the help of :- (1)Ethidium bromide in infrared radiation
- (2)Acetocarmine in bright blue light
- (3)Ethidium bromide in UV radiation
- (4)Acetocarmine in UV radiation
68.Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?- (1)Guanine, Adenine – Purines
- (2)Adenine, Thymine – Purines
- (3)Thymine, Uracil – Pyrimidines
- (4)Uracil, Cytosine – Pyrimidines
69.A molecule that can act as a genetic material must fulfil the traits given below, except- (1)It should be able to generate its replica
- (2)It should be unstable structurally and chemically
- (3)It should provide the scope for slow changes that are required for evolution
- (4)It should be able to express itself in the form of Mendelian characters.
70.In an E.coli strain i gene gets mutated and its product can not bind the inducer molecule. If growth medium is provided with lactose, what will be the outcome?- (1)z, y, a genes will be transcribed
- (2)z, y, a genes will not be translated
- (3)RNA polymerase will bind the promoter region
- (4)Only z gene will get transcribed
71.In eukaryotic cell transcription, RNA splicing and RNA capping takes place inside the- (1)Ribosomes
- (2)Nucleus
- (3)Dictyosomes
- (4)Endoplasmic Reticulum
72.The two polynucleotide chains in DNA are :- (1)Parallel
- (2)Discontinuous
- (3)Antiparallel
- (4)Semiconservative
73.In the history of biology, the human genome project led to the development of- (1)Biotechnology
- (2)Biomonitoring
- (3)Bioinformatics
- (4)Biosystematics
74.Which one of the following statements about the particular entity is true?- (1)Centromere is found in animal cells, which produces aster during cell division.
- (2)The gene for producing insulin is present in everyone’s cell.
- (3)Nucleosome is formed of nucleotides.
- (4)DNA consists of core of eight histones.
75.Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y gene?- (1)β-galactosidase
- (2)Lactose permease
- (3)Transacetylase
- (4)Lactose permease and Transacetylase
76.What are those structures that appear as ‘beads-on-string’ in the chromosomes when viewed under electron microscope?- (1)Nucleotides
- (2)Nucleosomes
- (3)Base pairs
- (4)Genes
77.Which one of the following also acts as a catalyst in a bacterial cell?- (1)snRNA
- (2)hnRNA
- (3)23S rRNA
- (4)5 S rRNA
78.The term 'Nuclein' for the genetic material was used by :- (1)Franklin
- (2)Meischer
- (3)Chargaff
- (4)Mendel
79.Gene regulation governing lactose operon of E. coli that involves the lacI gene product is- (1)Positive and inducible because it can be induced by lactose.
- (2)Negative and inducible because repressor protein prevents transcription.
- (3)Negative and repressible because repressor protein prevents transcription.
- (4)Feedback inhibition because excess of β galactosidase can switch off transcription.
80.If a DNA molecule is shortened by 25 base pairs, how many helical turns will be reduced from its structure?- (1)3
- (2)2.5
- (3)2
- (4)1
81.The commonly used vectors for human genome sequencing are- (1)T-DNA
- (2)BAC and YAC
- (3)Expression vectors
- (4)T/Cloning vectors
82.Which one of the following statement about histones is wrong?- (1)The pH of histones is slightly acidic.
- (2)Histones are rich in amino acids - Lysine and Arginine.
- (3)Histones carry positive charge in the side chain.
- (4)Histones are organized to form a unit of 8 molecules.
83.Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y-gene?- (1)Lactose permease and transacetylase
- (2)β-galactosidase
- (3)Lactose permease
- (4)Catalase
84.A single strand of nucleic acid tagged with a radioactive molecule is called- (1)Vector
- (2)Selectable market
- (3)Plasmid
- (4)Probe
85.If DNA contained sulphur instead of phosphorus and proteins contained phosphorus instead of sulfur, what would have been the outcome of Hershey and Chase experiment?- (1)No radioactive sulfur in bacterial cells
- (2)Both radioactive sulfur and phosphorus in bacterial cells
- (3)Radioactive sulfur in bacterial cells
- (4)Radioactive phosphorus in bacterial cells
86.Which of the following step cannot be considered as a process of regulation of gene expression in eukaryotes?- (1)Translational level
- (2)Transcriptional level
- (3)Replication level
- (4)Processing level
87.Which one of the following is not a part of a transcription unit in DNA?- (1)The inducer
- (2)A terminator
- (3)A promoter
- (4)The structural gene
88.Companion cells are closely associated with- (1)Sieve elements
- (2)Vessel elements
- (3)Trichomes
- (4)Guard cells
89.What initiation and termination factors are involved in transcription in prokaryotes?- (1)σ and ρ, respectively
- (2)α and β, respectively
- (3)β and γ, respectively
- (4)α and σ, respectively
90.One of the strands of double stranded DNA has base composition as follows : 15% A, 15% T, 40% G and 30% C. What will be the percentage of these bases in the complementary strand?- (1)15% A, .10% T, 40% G, 15% C
- (2)15% A, 15% T, 40% G, 30% C
- (3)15% A, 40% T, 15% G, 30% C
- (4)15% A, 15% T, 30% G, 40% C
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