NEET Previous Year Question

Cyclosporin A, used as immuno suppression agent, is produced from :

Topic: NEET PYQ

Answer: D. Full step-by-step solution below.

  1. AMonascus purpureus
  2. BSaccharomyces cerevisiae
  3. CPenicillium notatum
  4. DTrichoderma polysporum

Correct answer: D

Solution

(d) Production: Cyclosporin A is a cyclic non-ribosomal peptide metabolite produced through the fermentation of the filamentous fungus Trichoderma polysporum.
Function: It functions as a calcineurin inhibitor, which suppresses the activation of T-cells in the immune system.
Medical Use: It is critical in organ transplantation (kidney, liver, heart) to stop the body from attacking the newly grafted tissue.

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